Etudes cliniques

A phase 3, randomized, double-blind, controlled study evaluating the efficacy and safety of VX-445 combination therapy in subjects with cystic fibrosis who are heterozygous for the F508del mutation and a minimal function mutation (F/MF)

Effets de la réduction endoscopique du volume pulmonaire sur l’endurance à l’effort et l’hyperinflation bronchique chez le patient emphysémateux sévère

Evaluation of CFTR function in cultured organoids from rectal biopsies in patients with cystic fibrosis

A phase 3, open label, randomised, multi-centre, international study of MEDI4736, versus standard of care in patients with locally advanced or metastatic non-small cell lung cancer (stage IIIB-IV) who have received at least two prior systemic treatment regimens including one platinum-based chemotherapy regimen and do not have known EGFR TK activating mutations or ALK rearrangements (ARCTIC)

A randomized, blinded, parallel group, multi-center dose- finding study, to assess the efficacy, safety and tolerability of different doses of Tobramycin inhalation powder in patients with Non-Cystic Fibrosis Bronchiectasis and pulmonary P. aeruginosa infection

A 24-week, double-blind, randomized, parallel-group study evaluating the efficacy and safety of oral nintedanib coadministered with oral sildenafil, compared to treatment with nintedanib alone, in patients with idiopathic pulmonary fibrosis (IPF) and advanced lung function impairment

Un registre prospectif d'observation pour décrire l'évolution de la maladie et les résultats cliniques chez les patients atteints de fibrose pulmonaire idiopathique dans un environnement clinique réel

A double blind, randomized, placebo-controlled trial evaluating the efficacy and safety of nintedanib over 52 weeks in patients with progressive fibrosing interstitial lung disease (PF-ILD)

A multicenter, randomized, 52-week, double-blind, parallel-group, active controlled study to compare the efficacy and safety of QVM149 with QMF149 in patients with asthma