A phase III study of pembrolizumab versus best supportive care as second-line therapy in subjects with previously systemically treated advaced hepatocellular carcinoma
Phase 3b randomized trial comparing irradiation plus long term adjuvant androgen deprivation with GnRH antagonist versus GnRH agonist plus flare protection in patients with very high risk localized or locally advanced prostate cancer. A joint study of the EORTC ROG and GUCG
A phase 2 randomized open-label study of oral ODM-201 vs. androgen deprivation therapy (ADT) with LHRH agonists or antagonist in men with hormone naive prostate cancer
A randomized, double-blind, placebo controlled phase3 study of ODM 201 versus placebo in addition to standard androgen deprivation therapy and docetaxel in patients with metastatic hormone sensitive prostate cancer
A phase 3, multinational, randomised, open-label, parallel-arm study of avelumab (MSB0010718C) in combination with axitinib (INLYTA®) versus sunitinib (SUTENT®) monotherapy in the first-line treatment of patients with advanced renal cell carcinoma
A phase 3, multicenter, multinational, randomized, open-label, parallel-arm study of avelumab (MSB0010718C) plus best supportive care versus best supportive care alone as a maintenance treatment in patients with locally advanced or metastatic urothelial cancer whose disease did not progress after completion of first-line platinum-containing chemotherapy (Javelin Bladder 100)
A retrospective, international, multicentre study to describe the duration of routine treatment with abiraterone acetate in metastatic castration-resistant prostate cancer (mCRPC) patients without prior chemotherapy
Randomized multicenters phase 3 trial comparing enzalutamide vs a combination of Ra223 and enzalutamide in asymptomatic or mildly symptomatic castration resistant prostate cancer patients metastatic to bone. PEACE III
A phase 3 randomized, placebo-controlled double-blind study of JNJ-56021927 in combination with abiraterone acetate and prednisone Versus abiraterone acetate and prednisone in subjects with chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC)
PROSPER: A multinational, phase 3, randomized, double-blind, placebo-controlled, efficacy and safety study of enzalutamide in patients with nonmetastatic castration-resistant prostate cancer
A randomised, double blind, multicenter, parallel-group, phase 3 study to evaluate efficacy and safety of DCVAC/Pca versus placebo in men with metastatic castration resistant prostate cancer eligible for 1st line chemotherapy
A multicenter, single-arm, open-label, post-marketing safety study to evaluate the risk of seizure among subjects with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide who are at potential increased risk of seizure
A phase 3, open label, randomised, multi-centre, international study of MEDI4736, versus standard of care in patients with locally advanced or metastatic non-small cell lung cancer (stage IIIB-IV) who have received at least two prior systemic treatment regimens including one platinum-based chemotherapy regimen and do not have known EGFR TK activating mutations or ALK rearrangements (ARCTIC)
A european prospective observational study assessing the effectiveness and outcomes associated with enzalutamide treatment in patients with metastatic castration resistant prostate cancer (mCRPC). Premise
A randomised, double-blind, parallel group, placebo-controlled multicentre phase 3 study to assess the efficacy and safety of olaparib versus placebo as adjuvant treatment in patients with germline BRCA1/2 mutations and high risk HER2 negative primary breast cancer who have completed definitive local treatment and neoadjuvant or adjuvant chemotherapy (OLYMPIA Study)